Unlocking the Power of Spatial Omics:
Innovative Technologies and Advanced Data Analysis


Bruker Spatial Biology and the Applied Spatial Omics Centre (ASOC) jointly host the first Spatial Omics Seminar on Spatial Transcriptomics (ST), a groundbreaking method in Life Sciences. ST is a fascinating technique that helps Scientists understand how genes operate within different tissue parts. For example, you're reading a city map and uncovering each neighbourhood's unique characteristics and activities. In the same way, ST allows us to investigate which genes are “active” in specific areas of a sample, revealing insights that can lead to discoveries in Life Science.
During the Seminar, you will learn about the latest tools and techniques used in ST, focusing on GeoMx® DSP (Digital Spatial Profiler), CosMx® SMI (Spatial Molecular Imager), AtoMx® Spatial Informatics Platform (SIP), and the newest Spatial Proteomics platform, CellScape™, from the Bruker Spatial Biology. The Seminar will include lectures and demonstrations covering ST experiments, from sequencing to data preprocessing, analysis, and visualization.




Register

    RSVP to Secure a Complementary Lunch Closed

Venue

Speakers

  Jonathan Epp, PhD
Associate Profesor,
Dep. of Cell Biology and Anatomy,
University of Calgary		 Wes Heydeck, PhD
Sr. Field Application Scientist,
Bruker Spatial Biology
Bo Young Ahn, PhD
Sr. Spatial Biology Specialist,
Applied Spatial Omics Centre,
University of Calgary		 Heewon Seo, MS, PhD
Lead Bioinformatician,
Applied Spatial Omics Centre,
University of Calgary

Agenda

    Time Title Speaker
    10:00 - 10:50 High Plex, Multi-Omic Spatial Biology Capabilities at
    Bruker to Transform your Research.    		 Wes Heydeck, PhD
    10:50 - 11:20 Advancing Spatial Biology: Spatial Transcriptomics and
    ASOC Service Overview.    		 Bo Young Ahn, PhD
    11:20 - 12:00 Impaired Parvalbumin Interneurons in the Retrosplenial Cortex as
    the Root of Sex-Dependent Vulnerability in Alzheimer's Disease.    		 Jonathan Epp, PhD
    12:00 - 13:00 Lunch Break
         		  
    13:00 - 13:30 AtoMx Spatial Informatics Platform Deep Dive.
         		 Wes Heydeck, PhD
    13:30 - 15:00 Case study: Characterization of the Parvalbumin Interneurons in
    Mouse Brain using GeoMx DSP    		 Heewon Seo, MS, PhD

About Platforms from Bruker Spatial Biology

  1. GeoMx® DSP is the most flexible and robust spatial multi-omic platform for the analysis of formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue sections. GeoMx is the only spatial biology platform that non-destructively profiles the expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. It uses fluorescent imaging reagents to visualize tissue and oligo-tagged reagents for expression analysis. After selecting regions of interest (ROI), DNA oligos are released, and collected in a 96-well plate. Expression levels are readout using Next-Generation Sequencing (NGS) or nCounter and analyzed using the DSP interactive software.
    For more information, please visit Overview on Nanostring.com and Spatial Biology Revealed with the GeoMx DSP by NanoString on YouTube.

  2. CosMx® SMI is the first high-plex in situ analysis platform to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution. It enables rapid quantification and visualization of up to 1,000 RNA and 64 validated protein analytes and is the flexible, spatial single-cell imaging platform for cell atlasing, tissue phenotyping, cell-cell interactions, cellular processes, and biomarker discovery.
    For more information, please visit Overview on Nanostring.com and CosMx Spatial Molecular Imager by NanoString on YouTube.

  3. AtoMx® SIP is an integrated, cloud computing platform for spatial biology that can be used to visualize, analyze, and export data from CosMx® Spatial Molecular Imager (SMI).
    For more information, please visit Overview on Nanostring.com and Introducing AtoMx Spatial Informatics Platform by NanoString on YouTube.

  4. CellScape™ is an end-to-end solution for highly multiplexed spatial-omics. Combining an advanced, purpose-built imaging system with easy-to-use fluidics for walk-away automation, the CellScape system accelerates exploration in the rapidly evolving field of spatial biology.
    For more information, please visit Overview on CanopyBiosciences.com and Introducing CellScape™ Precise Spatial Multiplexing by Canopy Biosciences on YouTube.

Host/Sponsor

                     

Unlocking the Power of Spatial Omics: Innovative Technologies and Advanced Data Analysis




Bruker Spatial Biology and the Applied Spatial Omics Centre (ASOC) jointly host the first Spatial Omics Seminar on Spatial Transcriptomics (ST), a groundbreaking method in Life Sciences. ST is a fascinating technique that helps Scientists understand how genes operate within different tissue parts. For example, you're reading a city map and uncovering each neighbourhood's unique characteristics and activities. In the same way, ST allows us to investigate which genes are “active” in specific areas of a sample, revealing insights that can lead to discoveries in Life Science.
During the Seminar, you will learn about the latest tools and techniques used in ST, focusing on GeoMx® DSP (Digital Spatial Profiler), CosMx® SMI (Spatial Molecular Imager), AtoMx® Spatial Informatics Platform (SIP), and the newest Spatial Proteomics platform, CellScape™, from the Bruker Spatial Biology. The Seminar will include lectures and demonstrations covering ST experiments, from sequencing to data preprocessing, analysis, and visualization.


Register

    RSVP to Secure a Complementary Lunch Closed

Venue

Speakers

Jonathan Epp, PhD
Associate Profesor,
Dep. of Cell Biology and Anatomy,
University of Calgary
Wes Heydeck, PhD
Sr. Field Application Scientist,
Bruker Spatial Biology
Bo Young Ahn, PhD
Sr. Spatial Biology Specialist,
Applied Spatial Omics Centre,
University of Calgary
Heewon Seo, MS, PhD
Lead Bioinformatician,
Applied Spatial Omics Centre,
University of Calgary

Agenda

Time Title Speaker
10:00 - 10:50 High Plex, Multi-Omic Spatial Biology Capabilities at
Bruker to Transform your Research.		 Wes Heydeck, PhD
10:50 - 11:20 Advancing Spatial Biology: Spatial Transcriptomics and
ASOC Service Overview.		 Bo Young Ahn, PhD
11:20 - 12:00 Impaired Parvalbumin Interneurons in the Retrosplenial Cortex
as the Root of Sex-Dependent Vulnerability in Alzheimer's Disease.		 Jonathan Epp, PhD
12:00 - 13:00 Lunch Break  
13:00 - 13:30 AtoMx Spatial Informatics Platform Deep Dive. Wes Heydeck, PhD
13:30 - 15:00 Case study: Characterization of the Parvalbumin Interneurons
in Mouse Brain using GeoMx DSP		 Heewon Seo, MS, PhD

About Platforms from Bruker Spatial Biology

  1. GeoMx® DSP is the most flexible and robust spatial multi-omic platform for the analysis of formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue sections. GeoMx is the only spatial biology platform that non-destructively profiles the expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. It uses fluorescent imaging reagents to visualize tissue and oligo-tagged reagents for expression analysis. After selecting regions of interest (ROI), DNA oligos are released, and collected in a 96-well plate. Expression levels are readout using Next-Generation Sequencing (NGS) or nCounter and analyzed using the DSP interactive software.

    For more information, please visit Overview on Nanostring.com and Spatial Biology Revealed with the GeoMx DSP by NanoString on YouTube.

  2. CosMx® SMI is the first high-plex in situ analysis platform to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution. It enables rapid quantification and visualization of up to 1,000 RNA and 64 validated protein analytes and is the flexible, spatial single-cell imaging platform for cell atlasing, tissue phenotyping, cell-cell interactions, cellular processes, and biomarker discovery.

    For more information, please visit Overview on Nanostring.com and CosMx Spatial Molecular Imager by NanoString on YouTube.

  3. AtoMx® SIP is an integrated, cloud computing platform for spatial biology that can be used to visualize, analyze, and export data from CosMx® Spatial Molecular Imager (SMI).

    For more information, please visit Overview on Nanostring.com and Introducing AtoMx Spatial Informatics Platform by NanoString on YouTube.

  4. CellScape™ is an end-to-end solution for highly multiplexed spatial-omics. Combining an advanced, purpose-built imaging system with easy-to-use fluidics for walk-away automation, the CellScape system accelerates exploration in the rapidly evolving field of spatial biology..

    For more information, please visit Overview on CanopyBiosciences.com and Introducing CellScape™ Precise Spatial Multiplexing by Canopy Biosciences on YouTube.

Host/Sponsor