Applications of Spatial TranscriptomicsThe first Spatial Omics Seminar is jointly hosted by Bruker Spatial Biology and the Applied Spatial Omics Centre. Spatial Omics platforms allow researchers to profile the transcriptome in a spatial context. This seminar will introduce the participants to the applications of Spatial Omics, focusing on GeoMx DSP (Digital Spatial Profiler), CosMx SMI (Spatial Molecular Imager), and AtoMx Spatial Informatics Platform (SIP). The seminar will include lectures and demonstrations covering Spatial Transcriptomics experiments, from sequencing data to preprocessing, analysis, and visualization. RegistrationTBDVenue
ScheduleTBDAbout Nanostring GeoMx DSPGeoMx DSP is the most flexible and robust spatial multi-omic platform for the analysis of formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue sections. GeoMx is the only spatial biology platform that non-destructively profiles the expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. It uses fluorescent imaging reagents to visualize tissue and oligo-tagged reagents for expression analysis. After selecting regions of interest (ROI), DNA oligos are released, and collected in a 96-well plate. Expression levels are readout using Next-Generation Sequencing (NGS) or nCounter and analyzed using the DSP interactive software. About Nanostring CosMx SMICosMx SMI is the first high-plex in situ analysis platform to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution. It enables rapid quantification and visualization of up to 1,000 RNA and 64 validated protein analytes and is the flexible, spatial single-cell imaging platform for cell atlasing, tissue phenotyping, cell-cell interactions, cellular processes, and biomarker discovery. About Nanostring AtoMx SIPAtoMx SIP is an integrated, cloud computing platform for spatial biology that can be used to visualize, analyze, and export data from CosMxâ„¢ Spatial Molecular Imager (SMI). |